Database Manager
University College London
United Kingdom

The Center for Pediatric Inherited and Rare Cardiovascular Disease at UCL Institute of Cardiovascular Science is dedicated to clinical and translational research in the field of rare pediatric cardiac conditions, including inherited heart muscle disease, inherited arrhythmias, aortopathies and pulmonary hypertension. Taking advantage of the unique clinical resource of the Center for Inherited Cardiovascular Diseases and the national Pulmonary Hypertension service at Great Ormond Street Hospital, and with funding from GOSHCC, the BHF, NIHR/MRC, Action Medical Researc/LifeArc, Max's Foundation and the Dinosaur Trust, the Group's research program is focused on the following major themes:

1) Using novel deep phenotyping techniques to identify children and adolescents at increased risk of sudden cardiac death

2) Identification of early and pre-clinical phenotypes, with the aim of developing novel therapies to halt disease progression and prevent disease expression

3) Clinical trials of investigational medicinal products for the treatment of rare and inherited cardiovascular disease

4) Creation of a large biorepository resource to enable further research into these rare conditions

During the past 25 years, the Center for Heart Muscle Disease has been a national referral center for myocardial diseases specializing in the diagnosis and management of inherited sudden death and heart failure syndromes. The group, led by Professor Perry M. Elliott, comprises clinical academics based at the newly built Barts Cardiac Centre, St Bartholomew's Hospital and research scientists located at UCL. The Center's clinical and research experience has fundamentally changed the way in which many inherited cardiovascular diseases are managed. Particular innovations and discoveries include the identification of new disease causing genes, the development of clinical risk stratification algorithms and the development of international guidelines on the management of heart muscle diseases.

Jointly the two Groups take advantage of the unique clinical resources of the Center for Inherited Cardiovascular Diseases service at Great Ormond Street Hospital and the UCL Inherited Cardiac Disease Unit at Barts Hospital.

Over the past 8 years the team has developed a world-leading consortium of international centers looking after children with heart muscle disease. The International Pediatric Hypertrophic Cardiomyopathy Consoritum (IPHCC) currently includes 42 centers worldwide and represents that largest research network supporting research on childhood heart muscle disease in the world.

This post is supported by a philanthropic donation from Tenaya therapeutics.

The post holder will support the expansion and ongoing data maintenance of the International Pediatric Hypertrophic Cardiomyopathy Consortium (IPHCC). They will additionally provide support to other research studies and coordinate activities of research teams across the UCL, GOSH and Barts sites.

You will be qualified to MSc or MResdegree and have experience of supporting research studies and database management. Familiarity with regulatory requirements and research governance is essential as is experience of working in a multidisciplinary clinical research team. You will have IT proficiency at advanced user level (spreadsheet, word processing, database, e-mail, web-based applications) and experience of handling and analyzing complex datasets.

As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/